|
Irritable Bowel Syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
No evidence supported the association of GNβ3 rs5443, TNFα rs1800629, and IL10 rs1800871 to IBS in this study.
|
31615448 |
2019 |
|
Japanese Encephalitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
TNFA rs1800629 A and CCR5 rs1799987 A alleles were associated with susceptibility while combination lacking TNFA rs1800629 A, CCR5 rs333 Δ32, and rs1799987 A alleles and CCL2 rs1024611 G/G genotype was associated with protection to JE.
|
31479868 |
2019 |
|
Leukemia, Myelocytic, Acute
|
|
0.010 |
GeneticVariation
|
BEFREE |
We aimed to evaluate the multivariate effect of TNF-α rs361525, rs1800750, rs1800629, IL-10 rs1800896, rs1800872, IL-6 rs1800795, TGF-β1 rs1800470, IFN-γ rs2430561 single nucleotide polymorphisms (SNPs) on AML risk, the multivariate effect of SNPs on overall survival (OS) in AML and the association between the investigated SNPs and prognostic factors in AML.
|
31373163 |
2019 |
|
Coronary heart disease
|
|
0.030 |
GeneticVariation
|
BEFREE |
These results indicate that higher level of serum TNF-α increases risk of CHD, while TNF-α rs1800629 A allele might contribute to higher risk for CHD due to the increase in TNF-α expression.
|
31324728 |
2019 |
|
Respiratory Distress Syndrome, Adult
|
|
0.010 |
GeneticVariation
|
BEFREE |
The TNF-α rs1800629 locus A allele and the IL-6 rs1800796 locus G allele were found to be risk factors for ARDS (adjusted OR = 1.452, 95% CI: 1.211-1.689, P < .001 and adjusted OR = 1.205, 95% CI: 1.058-1.358, P = .005, respectively).
|
31261506 |
2019 |
|
Chronic Obstructive Airway Disease
|
|
0.040 |
GeneticVariation
|
BEFREE |
In contrast, the AA genotype carriers of the TNF-α rs1800629 has a significantly higher risk of developing COPD (OR = 1.83, 95%CI: (1.34-2.51), P < 0.00) compared to GG carrier.
|
31260854 |
2019 |
|
Sleep Apnea, Obstructive
|
|
0.020 |
GeneticVariation
|
BEFREE |
We found VWF rs1063856 (OR = 1.50, 95% CIs = 1.10-2.04; p = 0.010), IL-6 rs1800796 (OR = 1.32, 95% CIs = 1.11-1.56; p = 0.002), TNF rs1800629 (OR = 1.44, 95% CIs = 1.13-1.83; p = 0.003), and CRP rs2794521 (OR = 1.27, 95% CIs = 1.04-1.55; p = 0.021) were all significantly associated with increased susceptibility of OSA, while VWF rs1063856 (OR = 1.75, 95% CIs = 1.18-2.62; p = 0.006), IL-6 rs1800796 (OR = 1.39, 95% CIs = 1.10-1.76; p = 0.006) were associated with the severity of OSA.
|
31210414 |
2019 |
|
Psoriasis
|
|
0.020 |
GeneticVariation
|
BEFREE |
An association was found between rs1800629 (TNF-α) and Type I psoriasis, and rs833061 (VEGF) and Type II psoriasis.
|
31148856 |
2020 |
|
Glaucoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Thus present study aimed to analyze the association of TNF-α promoter region alterations (c.-238G>A (rs361525), c.-308G>A (rs1800629), c.-857C>T (rs1799724) and c.-863C>A (rs1800630)) with glaucoma in north Indian cohort.
|
31132515 |
2019 |
|
Diabetes Mellitus, Insulin-Dependent
|
|
0.040 |
GeneticVariation
|
BEFREE |
Our findings suggest that LTA rs909253 and TNF rs1800629 polymorphisms are associated with the risk of T1D both independently and in combination with polymorphic markers in other inflammatory genes, and the analysis of multi-allelic combinations provides valuable insight in the study of polygenic traits.
|
31054364 |
2019 |
|
Acute pancreatitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Epistasis analysis revealed that AP susceptibility was increased by interaction between <i>IL23R</i> rs11209026 and <i>TNF</i> rs1800629 (p = 1.205 × 10<sup>-5</sup>; OR<sub>interaction</sub> = 4.031).
|
31044631 |
2019 |
|
Acquired Immunodeficiency Syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
The association with A-G-A-C haplotype (beta = 0.718; standard error = 0.182; P = 0.0002) and with other 8.1AH-specific haplotypes including the high-producing tumor necrosis factor-alpha haplotype rs909253(G)-rs1800629(A) (beta = 0.308; standard error = 0.140; P = 0.032) were observed only with NHL identified as an AIDS-defining condition, but not as a post-AIDS condition, nor in combined AIDS and post-AIDS cases.
|
31026237 |
2019 |
|
Depressive Symptoms
|
|
0.020 |
GeneticVariation
|
BEFREE |
Considering the inflammatory-depression link, and that women are twice as likely to experience depression compared to men, the current study (<i>N</i> = 475 university students) examined the moderating role of three independent cytokine single nucleotide polymorphisms (SNPs; IL-1β rs16944, IL-6 rs1800795 SNP, TNF-α rs1800629) in the relationship between early-life adversity and depressive symptoms, and whether these relations differed between males and females.
|
30967802 |
2019 |
|
Mental Depression
|
|
0.010 |
GeneticVariation
|
BEFREE |
Considering the inflammatory-depression link, and that women are twice as likely to experience depression compared to men, the current study (<i>N</i> = 475 university students) examined the moderating role of three independent cytokine single nucleotide polymorphisms (SNPs; IL-1β rs16944, IL-6 rs1800795 SNP, TNF-α rs1800629) in the relationship between early-life adversity and depressive symptoms, and whether these relations differed between males and females.
|
30967802 |
2019 |
|
Depressed mood
|
|
0.010 |
GeneticVariation
|
BEFREE |
Considering the inflammatory-depression link, and that women are twice as likely to experience depression compared to men, the current study (<i>N</i> = 475 university students) examined the moderating role of three independent cytokine single nucleotide polymorphisms (SNPs; IL-1β rs16944, IL-6 rs1800795 SNP, TNF-α rs1800629) in the relationship between early-life adversity and depressive symptoms, and whether these relations differed between males and females.
|
30967802 |
2019 |
|
Depressive disorder
|
|
0.010 |
GeneticVariation
|
BEFREE |
Considering the inflammatory-depression link, and that women are twice as likely to experience depression compared to men, the current study (<i>N</i> = 475 university students) examined the moderating role of three independent cytokine single nucleotide polymorphisms (SNPs; IL-1β rs16944, IL-6 rs1800795 SNP, TNF-α rs1800629) in the relationship between early-life adversity and depressive symptoms, and whether these relations differed between males and females.
|
30967802 |
2019 |
|
Rheumatoid Arthritis
|
|
0.070 |
GeneticVariation
|
BEFREE |
Previous studies have investigated the association of TNF-α-238G/A (rs361525) and -308G/A (rs1800629) polymorphisms with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE).
|
30916218 |
2019 |
|
Lupus Erythematosus, Systemic
|
|
0.030 |
GeneticVariation
|
BEFREE |
Previous studies have investigated the association of TNF-α-238G/A (rs361525) and -308G/A (rs1800629) polymorphisms with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE).
|
30916218 |
2019 |
|
Kidney Failure, Acute
|
|
0.020 |
GeneticVariation
|
BEFREE |
Despite the numerous, although contradictory, studies about association between polymorphisms rs1800629 in <i>TNFA</i> and rs1800896 in <i>IL10</i> and AKI, we found no association (odds ratios 1.06 (95% CI 0.89⁻1.28, <i>p</i> = 0.51) and 0.92 (95% CI 0.80⁻1.05, <i>p</i> = 0.20), respectively).
|
30862128 |
2019 |
|
Malignant neoplasm of esophagus
|
|
0.020 |
GeneticVariation
|
BEFREE |
<b>Background</b>: TNF-α-308G/A (rs1800629) polymorphism has been previously implicated in the susceptibility to esophageal cancer, but results of these studies remained controversial or ambiguous.
|
30854115 |
2019 |
|
Esophageal carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
<b>Background</b>: TNF-α-308G/A (rs1800629) polymorphism has been previously implicated in the susceptibility to esophageal cancer, but results of these studies remained controversial or ambiguous.
|
30854115 |
2019 |
|
Esophageal Neoplasms
|
|
0.020 |
GeneticVariation
|
BEFREE |
<b>Background</b>: TNF-α-308G/A (rs1800629) polymorphism has been previously implicated in the susceptibility to esophageal cancer, but results of these studies remained controversial or ambiguous.
|
30854115 |
2019 |
|
Tuberculosis
|
|
0.020 |
GeneticVariation
|
BEFREE |
In addition, TNF rs1799724 and rs1800629 were associated with TB, but only in the Tibetan population.
|
30792445 |
2019 |
|
Age related macular degeneration
|
|
0.010 |
GeneticVariation
|
BEFREE |
To study polymorphisms in promotor regions of <i>tumor necrosis factor (TNF)-α TNF-863A/C</i> (rs1800630), <i>TNF-308A/G</i> (rs1800629), and <i>TNF-238A/G</i> (rs361525) in patients with age-related macular degeneration (AMD) and associations of complex <i>TNF-α</i> genotypes with AMD.
|
30662836 |
2019 |
|
Colorectal Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
Our analysis indicated no significant correlation between TNF-α-308G/A polymorphism (rs1800629) and CRC risk.
|
30610785 |
2019 |